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单卫星个人简介

  基本信息

  单卫星,男,博士,教授,博士研究生导师。从事分子植物病理学和真菌分子生物学的研究与教学工作。分别于1989.7和1992.7毕业于西北农业大学,获农学学士和硕士学位。1992.9-1995.12在西北农业大学植物保护系和中国科学院遗传研究所植物生物技术实验室联合培养博士研究生,获理学博士学位。

  1996.01-2001.04美国加州大学戴维斯分校,博士后;2001.05-2006.03澳大利亚国立大学,研究科学家(Research Fellow)。

  2005.09 -至今:西北农林科技大学植物病理学教授,博士研究生导师,从事卵菌生物学与作物卵菌病害成灾机理及病害防控研究。教育部长江学者特聘教授(2015-2019),国家杰出青年科学基金获得者(2012-2015),国家百千万人才工程国家级人选暨有突出贡献中青年专家(2013),教育部新世纪优秀人才支持计划(2006-2008)、陕西省“三秦学者”特聘教授(2011-2015)以及国家马铃薯产业技术体系岗位科学家(2009-2015);兼任中国植物病理学会理事(2014-)、中国菌物学会理事(2008-)、中国作物学会马铃薯专业委员会委员(2010-)以及陕西省农学会理事(2009-);《植物病理学报》、国际学术刊物《Frontiers in Plant Science》编委。

  在国家自然科学基金、科技部以及农业部项目的资助下,针对马铃薯晚疫病等作物重大病害,开展作物卵菌病害的应用与基础研究。在Cell、 New Phytologist、Molecular Plant-Microbe Interactions、Molecular Plant Pathology、Fungal Genetics and Biology、Frontiers in Plant Science、Plant Pathology等国际学术期刊发表论文20余篇。

  

      学术贡献

  首次克隆到卵菌的无毒基因--大豆疫霉菌 Avr1b ,在植物病原卵菌的寄主特异性研究方面取得突破;

  发现病原真菌效应蛋白存在类似RXLR的跨膜转运进入寄主细胞的功能结构域,证明了其转运无需病菌及其特化结构的存在;

  在揭示卵菌和真菌效应蛋白的转运机理方面取得突破:发现3-磷酸磷脂酰肌醇作为卵菌RXLR效应蛋白和真菌效应蛋白的受体分子介导其向寄主细胞的跨膜转运。

  学术荣誉

  教育部长江学者特聘教授(2015-2019)

  国家杰出青年科学基金获得者(2012-2015)

  国家百千万人才工程国家级人选暨有突出贡献中青年专家(2013)

  陕西省“三秦学者”特聘教授(2011-2015)

  教育部新世纪优秀人才(2006-2008)

  学术兼职

  中国植物病理学会理事(2014-)

  中国作物学会马铃薯专业委员会理事(2011-)

  中国菌物学会理事(2008-)

  陕西省农学会理事(2009-)

  湖北省作物病虫监测和安全控制重点实验室学术委员(2013-)

  《植物病理学报》编委(2015-)

  Review Editor, Frontiers in Plant Science, Frontiers in Microbiology(2011-)

  学术交流和大会报告情况

  泰山学术论坛(2015,青岛)

  The 9th World Potato Congress(2015, Beijing, China)

  海峡两岸植物病理学术研讨会(2015,台中)

  第四届全国生物入侵大会(2014,南宁)

  海峡两岸植物病理学青年科学家论坛(2013,北京)

  The 3rd International Conference on Biotic Plant Interactions (2013, Yangling, China)

  大会共同执行主席:中国科协第251次青年科学家论坛(2012,武汉)

  中国园艺学会2012年学术年会(2012,杨凌)

  第七届全国青年植保科技创新学术研讨会(2012,贵阳)

  The 2th International Conference on Biotic Plant Interactions (2011, Kunming, China)

  第九届中国植物病理学会全国会员代表大会暨2010年学术年会(2010,厦门)

  发表论文

 

  Kale, S. D., Gu, B., Capelluto, D. G. S., Dou, D., Feldman, E., Cronin, A., Arredondo, F. D., Fudal, I., Rouxel, T., Lawrence, C. B., Shan*, W., and Tyler*, B. M. 2010. External lipid PI3P mediates entry of eukaryotic pathogen effectors into plant and animal host cells. Cell 142: 284-295.

  Pan, Q. N., Cui, B. M., Deng, F. Y., Quan, J. L., Loake, G, and Shan*, W. 2016. RTP1 encodes a novel ER-localized protein in Arabidopsis and negatively regulates resistance against biotrophic pathogens. New Phytologist 209: 1641-1654.

  Zhu, Q. H., Shan, W., Ayliffe, M. A., Wang, M. B. 2016. Epigenetic mechanisms: An emerging player in plant-microbe interactions. Molecular Plant-Microbe Interactions 29:187-196.

  Tian, Y., Yin, J., Sun, J., Li, H., Ma, Y., Wang, Q., Quan, J., and Shan*, W. 2016. Population genetic analysis of Phytophthora infestans in northwestern China. Plant Pathology 65:17-25.

  Meng, Y., Huang, Y., Wang, Q., Wen, Q., Jia, J., Zhang, Q., Huang, G., Quan, J., and Shan*, W. 2015. Phenotypic and genetic characterization of resistance in Arabidopsis thaliana to the oomycete pathogen Phytophthora parasitica . Frontiers in Plant Science 6: 378.

  Meng. Y., Zhang, Q., Zhang, M., Gu, B., Huang, G., Wang, Q., and Shan*, W. 2015.The protein disulfide isomerase1 of Phytophthora parasitica (PpPDI1) is associated with the haustoria-like structures and contributes to plant infection. Frontiers in Plant Science 6: 632.

  Wang, Y., Cordewener, J. H. G., America, A. H. P., Shan, W., Bouwmeester, K., and Govers, F. 2015. Arabidopsis lectin receptor kinases LecRK-IX.1 and LecRK-IX.2 are functional analogs in regulating Phytophthora resistance and plant cell death. Molecular Plant-Microbe Interactions 28: 1032-1048.

  Tian, Y., Yin, J., Sun, J., Ma, H., Ma, Y., Quan, J., and Shan*, W. 2015. Population structure of the late blight pathogen Phytophthora infestans in a potato germplasm nursery in two consecutive years. Phytopathology 105: 771-777.

  Tian, Y., Sun, J., Li, H., Ma, Y., Liu, D, Quan, J., and Shan*, W. 2015. Genetic and phenotypic diversity analysis reveals dominance of a clonal lineage in the Phytophthora infestans from Northern Shaanxi, China. Plant Pathology 64: 200-206.

  Wang, Y., Bouwmeester, K., Patrick, B., Shan, W., and Govers, F. 2014. Phenotypic analyses of Arabidopsis T-DNA insertion lines and expression profiling reveal that multiple L-type lectin receptor kinases are involved in plant immunity. Molecular Plant-Microbe Interactions 27: 1390-1402.

  Meng, Y., Zhang, Q., Ding, W., and Shan*, W. 2014.  Phytophthora parasitica : a model oomycete plant pathogen. Mycology 5: 43-51.

  Wang, Y., Bouwmeester, K., van de Mortel, J. E., Shan, W., and Govers, F. 2013. Induced expression of defense-related genes in Arabidopsis upon infection with Phytophthora capsici . Plant Signaling & Behavior 8: e24618.

  Wang, Y., Bouwmeester, K., van de Mortel, J. E., Shan, W., and Govers, F. 2013. A novel Arabidopsis –oomycete pathosystem: differential interactions with Phytophthora capsici reveal a role for camalexin, indole glucosinolates and salicylic acid in defence. Plant, Cell & Environment 36: 1192-1203.

  Tyler, B. M., Kale, S. D., Wang, Q., Tao, K., Clark, H. R., Drews, K., Antignani, V., Rumore, A., Hayes, T., Plett, J. M., Fudal, I., Gu, B., Chen, Q., Affeldt, K. J., Berthier, E., Fischer, G. J., Dou, D., Shan, W., Keller, N. P., Martin, F., Rouxel, T., and Lawrence, C. B. 2013. Microbe-independent entry of oomycete RXLR effectors and fungal RXLR-Like effectors into plant and animal cells is specific and reproducible. Molecular Plant-Microbe Interactions 26: 611-616.

  Zhang, M., Meng, Y., Wang, Q., Liu D., Quan, J., Hardham, A. R., and Shan*, W. 2012. PnPMA1 , an atypical plasma membrane H+-ATPase, is required for zoospore development in Phytophthora parasitica . Fungal Biology 116: 1013-1023.

  Liu, J., Luo, S. Z., Zhang, Q., Wang, Q. H., Chen, J. F., Guo, A. G., and Shan*, W. 2012. Tn5 transposon mutagenesis in Acidovorax citrulli for identification of genes required for pathogenicity on cucumber. Plant Pathology 61: 364-374.

  Zhang, M., Wang, Q., Xu, K., Meng, Y., Quan, J., and Shan*, W. 2011. Production of dsRNA sequences in host plant is not sufficient to initiate gene silencing in the colonizing oomycete pathogen Phytophthora parasitica . PLoS ONE 6 (11): e28114.

  Gu, B., Kale, S. D.,  Wang, Q., Wang, D., Pan, Q., Cao, H., Meng, Y., Kang, Z. Tyler*, B. M., and Shan*, W. 2011. Rust secreted protein Ps87 is conserved in diverse fungal pathogens and contains a RXLR-like motif sufficient for translocation into plant cells. PLoS ONE 6 (11): e27217.

  Wang, Y., Meng, Y., Zhang, M., Tong, X., Wang, Q., Sun, Y., Quan, J., Govers, F., and Shan*, W. 2011. Infection of Arabidopsis thaliana by Phytophthora parasitica and identification of variation in host specificity. Molecular Plant Pathology 12: 187-201.

  Wang, Q., Han, C., Ferreira, A. O., Yu, X., Ye, W., Tripathy, S., Kale, S. D., Gu, B., Sheng, Y., Wang, X., Zhang, Z., Cheng, B., Dong, S., Shan, W., Zheng, X., Dou, D., Tyler, B. M., Wang, Y. 2011. Transcriptional programming and functional interactions within the Phytophthora sojae RXLR effector repertoire. Plant Cell 23: 2064-2086.

  Liu, T., Ye, W., Ru, Y., Yang, X., Gu, B., Tao, K., Lu, S. Dong, S., Zheng, X., Shan, W., Wang, Y., and Dou, D. 2011. Two host cytoplasmic effectors are required for pathogenesis of Phytophthora sojae by suppression of host defenses. Plant Physiology 155: 490-501.

  Narayan, R. D., Blackman, L. M., Shan, W., Hardham, A. R. 2010. Phytophthora nicotianae transformants lacking dynein light chain 1 produce non-flagellate zoospores.  Fungal Genetics and Biology 47: 663-671.

  Gan, P. H. P., Shan, W., Blackman, L. M., and Hardham, A. R. 2009. Characterization of cyclophilin-encoding genes in Phytophthora .  Molecular Genetics and Genomics 281: 565-578.

  Hardham, A.R. and Shan, W.  2009. Cellular and molecular biology of Phytophthora -plant interactions.  The Mycota,Plant Relationships V, Second Edition, edited by H.B. Deising.  Springer-Verlag, Berlin.  Pp. 3-27.

  Shan, W., Liu, J., and Hardham, A. R. 2006. Phytophthora nicotianae PnPMA1 encodes an atypical plasma membrane H+-ATPase that is functional in yeast and developmentally regulated.  Fungal Genetics and Biology 43: 583-592.

  Shan*, W., Marshall, J. S., and Hardham, A. R. 2004. Gene expression in germinated cysts of Phytophthora nicotianae .  Molecular Plant Pathology 5: 317-330.

  Shan, W. and Hardham, A. R. 2004. Construction of a bacterial artificial chromosome library, determination of genome size, and characterization of an Hsp70 gene family of Phytophthora nicotianae .  Fungal Genetics and Biology 41: 369-380.

  Shan, W.,Cao, H., Leung, D., and Tyler, B. M. 2004. The Avr1b locus of Phytophthora sojae encodes an elicitor and a regulator required for avirulence on soybean plants carrying resistance gene Rps 1b.  Molecular Plant-Microbe Interactions 17: 394-403.

  Chamnanpunt, J., Shan, W., and Tyler, B. M. 2001. High frequency mitotic gene conversion in genetic hybrids of the oomycete Phytophthora sojae . Proceedings of National Academy of Sciences USA 98: 14530-14535.

  马云芳,孙洁平,马丽杰,权军利,单卫星*. 2013. 一个马铃薯种质资源圃致病疫霉群体的分析. 菌物学报 32 (5):802-811.

  刘秋萍,姚茂金,马英,邓斌生,单卫星*. 2010. 拟南芥与大豆疫霉菌的非寄主互作及一个感病突变体的遗传分析. 植物学报 45 (5):548-555.

  殷丽华,王秦虎,宁峰,朱晓莹,左豫虎,单卫星*.2010.大豆疫霉菌一个DNA指纹分析重复序列探针的鉴定. 微生物学报 50 (4):524-529.

  哈霞,胡中慧,王蕾,权军利,单卫星*.2010.大豆疫霉菌的EMS化学诱变. 菌物学报29 (2):222-227.

  联系方式

  通讯地址:陕西杨凌邰城路3号 西北农林科技大学科研主楼1104室

  邮编:712100;电话:029-8708 0102;传真:029-8708 0062

  Email: wxshan@nwafu.edu.cn

  Web: www.oomycete.cn